Etiket - MDS

Myelodysplastic syndroms

The myelodysplastic syndromes (MDS, formerly known as “preleukemia”) are a diverse collection of hematological conditions united by ineffective production (or dysplasia) of myeloid blood cells and risk of transformation to acute myelogenous leukemia (AML).[1] Anemia requiring chronic blood transfusion is frequently present. Astronomer Carl Sagan, writer Roald Dahl, jazz saxophonist Michael Brecker and actress Nina Foch died of this condition. Myelodysplastic syndromes are bone marrow stem cell disorders resulting in disorderly and ineffective hematopoiesis (blood production) manifested by irreversible quantitative [...]

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